megatomi.com Secrets
megatomi.com Secrets
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Rapidly obtain sections as skinny or thick as your software involves, with out worrying about shedding or distorting useful tissue samples.
Megatome is usually a vibrating microtome designed to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits high-throughput tissue sectioning with uniform surface profile, in addition to minimum tissue hurt and data reduction.
Antibodies may well acquire months to diffuse through only a few millimeters of tissue, having a steep labeling gradient from floor to Main.
Megatome is created for precision: the blade vibrates at an increased frequency and bigger amplitude selection than other microtomes, and encompasses a unique deflection Handle system.
SE utilizes a rotational electric powered field to disperse very electromobile molecules (including antibodies or surfactant micelles) all through a porous sample without harming electrically charged buildings throughout the tissue. This permits 2-four working day clearing of intact organs,
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eFLASH is usually megatomi.com a quick tissue labeling technique that enables for uniform entire-organ staining in twenty rounds of labeling.
The SmartSPIM gentle sheet microscope provides unparalleled resolution and acquisition pace all through intact tissue volumes, when its modular style means that you can improve and customize person elements.
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Defend avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, guarding specimens for a number of rounds of processing.
Leverage the Obvious+ tissue clearing system, in addition to eFLASH and patented stochastic electrotransport systems, to swiftly apparent and label whole organs. Important highlights and characteristics include things like:
Our novel SHIELD tissue preservation method kinds intramolecular bonds employing polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.